The effect of a flooding dose of phenylalanine on indicators of metabolic status in pigs

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Abstract
The metabolic effect of infusing growing pigs with a large dose of phenylalanine was investigated. Packed cell volume and plasma glucose levels were not affected (P > 0.05), while plasma insulin concentration was increased at some time periods compared to a saline control (P < 0.05). For amino acids, only phenylalanine and tyrosine concentrations were increased (P < 0.05) by phenylalanine infusion. A flooding dose of phenylalanine may not significantly alter the metabolic status of the pig and could therefore be used in measuring protein synthesis in pigs. Key words: Amino acid, flooding dose, glucose, insulin, phenylalanine, pig

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