The activity of cefotaxime and desacetylcefotaxime against Bacteroides species compared to 7-methoxy cephems and other anti-anaerobe drugs
- 1 January 1984
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Antimicrobial Chemotherapy
- Vol. 14 (suppl B) , 39-43
- https://doi.org/10.1093/jac/14.suppl_b.39
Abstract
The combination of cefotaxime and desacetylcefotaxime was tested against 83 Bacteroides strains (seven species) isolated from several hospitals. The combination greatly enhanced the anti-anaerobic spectrum of cefotaxime: 79.7% of tested strains were synergistically killed by the combination. Although the combination appears clinically efficacious, it is only comparable to cefoxitin and still less active than clindamycin, chloramphenicol and metronidazole.Keywords
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