LEAD STUDIES
Open Access
- 1 August 1924
- journal article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 40 (2) , 151-172
- https://doi.org/10.1084/jem.40.2.151
Abstract
It appears, from the investigations in other laboratories, that the anemia observed in cases of lead poisoning is due to destruction of blood rather than to diminished production of blood. The method of poisoning cells in vitro with lead was adopted in order to study this phenomenon, and distinct effects were thereby obtained, even when only 0.001 mg. of lead is added to approximately 5 billion washed red corpuscles. In order to obtain optimum results the usual dosage employed was ten times this or 0.01 mg. per 5 billion cells. The following changes were observed in cells so treated.Keywords
This publication has 2 references indexed in Scilit:
- BLOOD DESTRUCTION DURING EXERCISEThe Journal of Experimental Medicine, 1922
- THE NORMAL FATE OF ERYTHROCYTESThe Journal of Experimental Medicine, 1917