THE ACTION OF ETHYLHYDROCUPREIN (OPTOCHIN) ON TYPE STRAINS OF PNEUMOCOCCI IN VITRO AND IN VIVO, AND ON SOME OTHER MICROORGANISMS IN VITRO
Open Access
- 1 September 1915
- journal article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 22 (3) , 269-285
- https://doi.org/10.1084/jem.22.3.269
Abstract
1. Ethylhydrocuprein hydrochloride in very high dilution inhibits the growth of, and in 18 hours kills, representatives of all four groups of pneumococci in vitro. The killing effect is generally seen in somewhat lower dilutions than the inhibiting effect. No constant or considerable difference is seen in these actions on representatives of the four groups of the pneumococci. The action of ethylhydrocuprein hydrochloride on the pneumococci in vitro is so strongly specific that it may possibly be used as a test for a true pneumococcus.Keywords
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