Nasal absorption of progesterone in women
- 1 January 1987
- journal article
- research article
- Published by Wiley in BJOG: An International Journal of Obstetrics and Gynaecology
- Vol. 94 (1) , 84-88
- https://doi.org/10.1111/j.1471-0528.1987.tb02258.x
Abstract
Summary. Absorption profiles were obtained from women following the administration of ointment containing 20, 30 and 40 mg of progesterone to the nasal mucosa. There were no significant differences in area-under-curves between groups receiving the drug in one nostril but when 40 mg doses were divided between two nostrils there was a significantly greater area-under-curve suggesting that the area of mucosa applied with the drug is more important than dosage.Keywords
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