A simple procedure has been outlined for isolating Schistosoma eggs from host liver tissue by a combination of comminution, filtration, and sedimentation through a viscous medium (sucrose). The resultant purified eggs retain certain normal qualities tested such as morphological integrity, hatchability, acid-fastness, ability to react with circumoval precipitins in immune serum, and ability to incite tissue reactions when injected into experimental animals. The procedure also provides for a degree of separation of fully mature eggs from other types, and for microscopic observation and some degree of control of the separation process.