Loss of Protection by Vaccination Following Cortisone Treatment in Mice with Experimentally Induced Tuberculosis

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Abstract
Treatment with cortisone overcame the beneficial effect of vaccination in mice infected with a highly virulent strain of Mycobacterium tuberculosis. human type, bud did not significantly enhance the lethality in nonvaccinated mice; it also increased the susceptibility of mice to infection with M. tuberculosis of reduced virulence.