Deficient Quantitative Expression of CD45 Isoforms on CD4+ and CD8+ T Cell Subpopulations and Subsets of CD45RAlowCD45ROlow T Cells in Newborn Blood
- 1 January 1996
- journal article
- research article
- Published by S. Karger AG in Neonatology
- Vol. 69 (2) , 128-132
- https://doi.org/10.1159/000244287
Abstract
Deficiencies in the quantitative expression of CD45RA and CD45RO on CD4+ and CD8+ T cells and in a population of CD45RAlowCD45ROlow T cells in blood from term newborn infants were found by flow cytometry. The relative frequencies of CD45RO on CD4+ T cells from adults and newborn infants were 72 and 58%, respectively. However, in newborn infants greater than 70% of T cells expressing CD45RO also expressed CD45RA. In addition, the quantitative expression of CD45RA and CD45RO on newborn T cells was significantly less than that found on adult blood T cells.Keywords
This publication has 0 references indexed in Scilit: