Neoangiogenesis in the peritoneal membrane: does it play a role in ultrafiltration failure?

Publisher Website
Google Scholar
Abstract
Long‐term preservation of peritoneal membrane function is a prerequisite for successful peritoneal dialysis (PD). The development of ultrafiltration failure (UFF) is the most important cause of technique failure next to recurrent peritonitis [ 1]. Its significance is likely to increase as the reduction in peritonitis rates makes PD a more viable option for a larger number of patients. The present overview briefly discusses the alterations in peritoneal membrane function that underlie loss of ultrafiltration capacity. In addition, the structural changes observed in the peritoneum of long‐term PD patients will be addressed. Finally, an attempt will be made to provide a link between the functional and morphological alterations.