Recombinant Human Activated Protein C for the Postexposure Treatment of Ebola Hemorrhagic Fever
Open Access
- 15 November 2007
- journal article
- Published by Oxford University Press (OUP) in The Journal of Infectious Diseases
- Vol. 196 (s2) , S390-S399
- https://doi.org/10.1086/520598
Abstract
Background. Infection of primates with Zaire ebolavirus (ZEBOV) leads to hypotension, coagulation disorders, and an impaired immune response and, inKeywords
This publication has 45 references indexed in Scilit:
- Development of treatment strategies to combat Ebola and Marburg virusesExpert Review of Anti-infective Therapy, 2006
- Septic shockPublished by Elsevier ,2005
- Exotic emerging viral diseases: progress and challengesNature Medicine, 2004
- Analysis of Human Peripheral Blood Samples from Fatal and Nonfatal Cases of Ebola (Sudan) Hemorrhagic Fever: Cellular Responses, Virus Load, and Nitric Oxide LevelsJournal of Virology, 2004
- Pathogenesis of Ebola Hemorrhagic Fever in Cynomolgus MacaquesThe American Journal of Pathology, 2003
- Mechanisms Underlying Coagulation Abnormalities in Ebola Hemorrhagic Fever: Overexpression of Tissue Factor in Primate Monocytes/Macrophages Is a Key EventThe Journal of Infectious Diseases, 2003
- Ebola Hemorrhagic Fever and Septic ShockThe Journal of Infectious Diseases, 2003
- Inflammatory responses in Ebola virus-infected patientsClinical and Experimental Immunology, 2002
- Proinflammatory response during Ebola virus infection of primate models: possible involvement of the tumor necrosis factor receptor superfamilyImmunology Letters, 2002
- Markedly Elevated Levels of Interferon (IFN)‐σ, IFN‐α, Interleukin (IL)‐2, IL‐10, and Tumor Necrosis Factor‐α Associated with Fatal Ebola Virus InfectionThe Journal of Infectious Diseases, 1999