The effect of varying spatial resolution on the detectability of diffuse pulmonary nodules. Assessment with digitized conventional radiographs.

Abstract
Detection and discrimination of [human] miliary disease and small pulmonary nodules were tested at 6 levels of spatial resolution varying between 0.3-2.5 I.p./mm and receiver operating characteristic (ROC) curves were generated. The test images were obtained by digitizing selected normal and abnormal standard film/screen radiographs. Although there was no statistically significant difference in observer performance between 0.5-2.5 I.p./mm, the findings may have clinical relevance. Further observer detection studies of different disease processes are planned to help formulate performance standards for an electronic digital radiographic device for chest imaging.