STUDIES ON CROSS-RESISTANCE BETWEEN CAPREOMYCIN AND CERTAIN OTHER ANTI-MYCOBACTERIAL AGENTS
- 1 January 1963
- journal article
- Published by Editorial Committee of Japanese Journal of Infectious Diseases, National Institute of Infectious Dis in Japanese Journal of Medical Science and Biology
- Vol. 16 (1) , 31-38
- https://doi.org/10.7883/yoken1952.16.31
Abstract
Capreomycin, originally called capromycin, is a new antibiotic which was isolated from Streptomyces capreolus in the laboratories of Eli Lilly & Co. Herr et al. (1961, 1962) reported that this peptide antibiotic, with a molecular weight of approximately 740, was active primarily against Mycobacteria, and cross-resistance was not recognized between capreomycin and streptomycin or viomycin in vitro. On the other hand, Robinson and Wichelhausen (1962) noted some differences in the susceptibility to capreomycin of the wild strains tested. These reports, however, did not include a detailed analysis of the cross-resistance with capreomycin. This paper presents results of cross-resistance experiments on capreomycin and some clinically important antimycobacterial agents, employing human tubercle bacilli and M. phlei.Keywords
This publication has 3 references indexed in Scilit:
- THE ANTITUBERCULOUS ACTIVITY OF KANAMYCIN IN VITRO AND IN THE EXPERIMENTAL ANIMAL (GUINEA PIG)*Annals of the New York Academy of Sciences, 2006
- Cross-Resistance Studies with Neomycin AntibioticsNature, 1962
- Similarity of Albomycin and GriseinScience, 1957