Mechanism of Joint Toxic Action of Kitazin P[○!R] with Malathion in the Malathion Resistant Green Rice Leafhopper, Nephotetiix cincticeps UHLER (Hemiptera : Deltocephalidae)

Abstract
The mechanism of joint toxic action of Kitazin-P [organophosphorus fungicide] with malathion in the resistant green rice leafhopper was studied. From the toxicity test, high joint toxic action was observed only in resistant strains but not in susceptible ones. Kitazin-P showed no effect on acetylcholinesterase inhibition by malaoxon in vitro. 14C-methyl malathion degradation in vitro was higher in resistant strains than in susceptible ones; this was 1 of the main resistance factors. Kiazin-P showed a strong inhibitory action on malathion degradation. Kitazin-P apparently inhibits malathion degrading carboxylesterase.

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