Production of Migration Inhibitory Factor by Non-Dividing Lymphocytes
Open Access
- 1 March 1973
- journal article
- Published by Oxford University Press (OUP) in The Journal of Immunology
- Vol. 110 (3) , 674-678
- https://doi.org/10.4049/jimmunol.110.3.674
Abstract
Lymphocyte proliferation in response to antigen was essentially eliminated by treatment with 5-bromo-2-deoxyuridine and light. The remaining lymphocytes were restimulated with the same antigen and the production of migration inhibitory factor (MIF) was determined. Under these conditions, MIF activity was still present. In addition, the absence of dividing cells did not appear to diminish significantly the amount of MIF produced.Keywords
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