Immunological cross-reactivity between outer membrane pore proteins of Campylobacter jejuni and Escherichia coli
- 1 December 1992
- journal article
- research article
- Published by Oxford University Press (OUP) in FEMS Microbiology Letters
- Vol. 99 (2-3) , 281-285
- https://doi.org/10.1016/0378-1097(92)90041-l
Abstract
Immunocrossreactivity between the major outer membrane protein (MOMP) of Campylobacter jejuni 85H and the OmpC porin of Escherichia coli K-12 was observed. These results indicate that a common antigenic domain is conserved in both MOMP and OmpC. This antigenic region is detected only after a 96°C treatment suggesting that it is buried in the native conformation of the respective porins. In addition, differences were observed between the major outer membrane proteins from various C. jejuni strains tested contained a protein exhibiting a similar electrophoretic profile to the 85H porin.Keywords
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