Curare-Like Drugs and Vagal Synapses: Comparative Study in vitro on the Isolated Vagus-Stomach Preparation of the Rat

Abstract
The anti-acetylcholine properties of curare-like drugs have been investigated on the motor responses of the electrically stimulated isolated vagus-stomach preparation of the rat. The synaptic site of the inhibitory action shown to varying degrees by the compounds tested has been located by comparing the modifications of the gastric responses to stimulation of preganglionic vagal fibres with the unmodified responses of the rat stomach strip preparation to acetylcholine.