Development of predictive pharmacokinetic simulation models for drug discovery

This publication has 22 references indexed in Scilit:

• Managing the drug discovery/development interface
  Drug Discovery Today, 1997
• Simulation models to predict oral drug absorption from in vitro data
  Advanced Drug Delivery Reviews, 1997
• Novel Approach to the Analysis of in Vitro–in Vivo Relationships**Presented in part at the Ninth Annual Meeting and Exposition of the American Association of Pharmaceutical Scientists, San Diego, CA, November 1994.
  Journal of Pharmaceutical Sciences, 1996
• Effect of Food on the Relative Bioavailability of Oral Ganciclovir
  The Journal of Clinical Pharmacology, 1996
• Ganciclovir absolute bioavailability and steady-state pharmacokinetics after oral administration of two 3000-mg/d dosing regimens in human immunodeficiency virus— and cytomegalovirus-seropositive patients
  Clinical Therapeutics, 1995
• Pharmacokinetic, Safety, and Antiviral Profiles of Oral Ganciclovir in Persons Infected with Human Immunodeficiency Virus: A Phase I/II Study
  The Journal of Infectious Diseases, 1995
• In Vitro Dissolution Tests Corresponding to the in Vivo Dissolution of Clarithromycin Tablets in the Stomach and Intestine.
  CHEMICAL & PHARMACEUTICAL BULLETIN, 1995
• Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells
  Biochemical and Biophysical Research Communications, 1991
• Absorption Potential: Estimating the Fraction Absorbed for Orally Administered Compounds
  Journal of Pharmaceutical Sciences, 1985
• Pharmacokinetic studies with atenolol in the dog
  Biopharmaceutics & Drug Disposition, 1983