Metabolic control theory: its role in microbiology and biotechnology
- 1 October 1986
- journal article
- Published by Oxford University Press (OUP) in FEMS Microbiology Letters
- Vol. 39 (4) , 305-320
- https://doi.org/10.1016/0378-1097(86)90020-0
Abstract
Many areas of microbiology and biotechnology are directly concerned with the isolation, study or engineering of cells capable of (over)producing metabolites of commercial significance. Yet the study, production or improvement of such strains has often been at best semi-empirical. The metabolic control theory developed by Kacser, Burns, Heinrich and Rapoport can provide a rational and quantitative basis for the description and improvement of such processes.Keywords
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