Mechanism of Corneal Permeation of L-Valyl Ester of Acyclovir: Targeting the Oligopeptide Transporter on the Rabbit Cornea
- 1 January 2002
- journal article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 19 (8) , 1194-1202
- https://doi.org/10.1023/a:1019806411610
Abstract
Purpose. To delineate mechanisms associated with the corneal transport of a L-valine prodrug of an antiviral agent, acyclovir. Method.The permeability and enzymatic hydrolysis of L-Val-ACV were...Keywords
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