Radiation Retinopathy

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Abstract
To the Editor. —The recent reply from Kinyoun and Orcutt1expressing concern that "a recent Letter to the Editor published inJAMA2does not accurately state the effectiveness and risk of radiation treatment" of Graves' ophthalmopathy is itself inaccurate and misleading. We are unable to document a single instance in which retinopathy can be attributed to therapy with a total dose of 2000 cGy when delivered in daily increments of 180 to 200 cGy. This includes patients irradiated at the authors' own current location, the University of Washington, Seattle, between 1958 and 1977. The patients they referred to as those developing "radiation retinopathy" received a total dose in excess of 3500 cGy that was given in large daily increments (in excess of 350 cGy), a method of administration that has clearly been documented as a major incriminating factor in radiation damage of the central nervous system and the

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