Malacoplakia of the Prostate Confused with Clear Cell Carcinoma

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Abstract
Primary malacoplakia of the prostate is a rare benign disease, which is frequently mistaken for carcinoma and granulomatous prostatitis. The surgical and clinical course of a patient with obstructive hypertrophy of the prostate is reviewed after an initial incorrect diagnosis of clear cell carcinoma. Experience in defining the lesion during transurethral resection is presented. The pathogenesis, morphological structure and unique microscope appearance of malacoplakia, characterized by large mononuclear cells associated with small laminated concretions, are described and illustrated.