Structural changes required for activation of protein C are induced by Ca2+ binding to a high affinity site that does not contain gamma-carboxyglutamic acid.

This publication has 18 references indexed in Scilit:

• Interaction of calcium with bovine plasma protein C
  Biochemistry, 1981
• Blood Coagulation
  Annual Review of Biochemistry, 1980
• Zymogens and Cofactors of Blood Coagulatio
  Critical Reviews in Biochemistry, 1980
• The inhibition of blood coagulation by activated protein C through the selective inactivation of activated factor V
  Biochimica et Biophysica Acta (BBA) - Enzymology, 1979
• Lanthanides as probes for calcium in biological systems
  Quarterly Reviews of Biophysics, 1979
• Anticoagulant properties of bovine plasma protein C following activation by thrombin
  Biochemistry, 1977
• Vitamin K-Dependent Formation of γ-Carboxyglutamic Acid
  Annual Review of Biochemistry, 1977
• Proteolytic activation of protein C from bovine plasma
  Biochemistry, 1976
• A new approach to the calculation of secondary structures of globular proteins by optical rotatory dispersion and circular dichroism
  Biochemical and Biophysical Research Communications, 1971
• THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS
  Annals of the New York Academy of Sciences, 1949