Disruption of Mitochondrial Malate-Aspartate Shuttle Activity in Mouse Blastocysts Impairs Viability and Fetal Growth1
Open Access
- 1 February 2009
- journal article
- research article
- Published by Oxford University Press (OUP) in Biology of Reproduction
- Vol. 80 (2) , 295-301
- https://doi.org/10.1095/biolreprod.108.069864
Abstract
The nutrient requirements and metabolic pathways used by the developing embryo transition from predominantly pyruvate during early cleavage stages toKeywords
This publication has 35 references indexed in Scilit:
- To QC or not to QC: the key to a consistent laboratory?Reproduction, Fertility and Development, 2008
- Effect of culturing mouse embryos under different oxygen concentrations on subsequent fetal and placental developmentThe Journal of Physiology, 2006
- Response characteristics of the mitochondrial DNA genome in developmental health and diseaseBirth Defects Research Part C: Embryo Today: Reviews, 2004
- Role of developmental factors in the switch from pyruvate to glucose as the major exogenous energy substrate in the preimplantation mouse embryoReproduction, Fertility and Development, 1999
- Analysis of stimulatory and inhibitory amino acids for development of hamster one‐cell embryos in vitroMolecular Reproduction and Development, 1995
- Role of glucose in mouse preimplantation embryo developmentMolecular Reproduction and Development, 1995
- Culture of preimplantation embryos: facts and artifactsHuman Reproduction Update, 1995
- Uptake and metabolism of pyruvate and glucose by individual sheep preattachment embryos developed in vivoMolecular Reproduction and Development, 1993
- Aspartate aminotransferase, malate dehydrogenase, and pyruvate carboxylase activities in rat cerebral synaptic and nonsynaptic mitochondria: Effects ofin vitro treatment with ammonia, hyperammonemia and hepatic encephalopathyMetabolic Brain Disease, 1991
- Possibility for the Transfer of Reducing Equivalents from the Cytosol to the Mitochondrial Compartment in Ehrlich Ascites Tumor Cells by the Malate‐Aspartate ShuttleEuropean Journal of Biochemistry, 1972