EFFECTS OF GIVING WATER 20–450 ML WITH ORAL DIAZEPAM PREMEDICATION 1–02 H BEFORE OPERATION

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Abstract
We have studied the volume of water which should accompany diazepam 10mg oral premedication given 1–2 h before induction of anaesthesia in 75 patients undergoing elective gynaecological laparoscopy. Twenty-five patients were given 20 ml (group A), 25 patients 150 ml (group B), and 25 patients 300–450 ml of water (group C). There were no differences between the groups in gastric fluid volume and acidity. All groups reported a reduction in thirst and dryness of the mouth after water intake, while only group B reported significant anxiolysis. Eight patients in group C experienced augmented diuresis, compared with no patients in groups A and B. We conclude that 150 ml is the ideal amount of water given with oral prernedication 1–2 h before anaesthesia. (Br. J. Anaesth. 1993; 71: 503–506)

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