Effects of Alexidine·2HCl Mouthwash on Plaque and Gingivitis after six Months
- 1 November 1977
- journal article
- clinical trial
- Published by SAGE Publications in Journal of Dental Research
- Vol. 56 (11) , 1349-1358
- https://doi.org/10.1177/00220345770560111101
Abstract
Two-hundred and fourteen subjects ranging in age from 22 to 63 years used either a mouthwash that contained 0.035% w/v alexidine· 2HCl (2-ethylhexyl bisbiguanidine dihydrochloride) or a placebo twice daily on a double-blind basis for six months in conjunction with routine oral hygiene procedures. The results indicated that alexidine·2HCl was safe and was statistically more effective in producing a clinically significant reduction in gingivitis than was the placebo.Keywords
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