Precipitin Production in Chickens
Open Access
- 1 October 1952
- journal article
- Published by Oxford University Press (OUP) in The Journal of Immunology
- Vol. 69 (4) , 423-434
- https://doi.org/10.4049/jimmunol.69.4.423
Abstract
Summary: The similarity of pheasant and owl antibeef-albumin precipitins to chicken precipitins was demonstrated. At low salinity, about 1%, precipitation of these antibodies was very incomplete; on increasing the salinity the precipitation became more complete. The inhibition of precipitation in low salinity could readily be reversed by raising the sodium-chloride content of the reaction mixtures. Conversely, the maximal precipitates formed in high salinity, 8% to 12%, could be partially dissolved by resuspension in 1% saline. The precipitation patterns were interpreted primarily in terms of a decrease of the dissociability of the initially formed antigen-antibody compounds on increasing the salinity of the reaction mixtures.Keywords
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