Intracellular immunoglobulin distribution of bone marrow plasma cells as a diagnostic aid for primary amyloidosis.
Open Access
- 1 March 1982
- journal article
- research article
- Published by BMJ in Journal of Clinical Pathology
- Vol. 35 (3) , 285-288
- https://doi.org/10.1136/jcp.35.3.285
Abstract
In order to classify the underlying disorder in four patients with biopsy-proven amyloidosis without overt monoclonal gammopathy, the cytoplasmic immunoglobulin (Ig) distribution of bone marrow plasma cells was evaluated using direct immunofluorescence microscopy. This procedure revealed the presence of a monoclonal proliferation of light chain containing plasma cells, and thus led to the diagnosis of immunoglobulin-related amyloidosis.This publication has 16 references indexed in Scilit:
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