Comparison of continuous and intermittent administration of extradural bupivacaine for analgesia after lower abdominal surgery
- 1 January 1998
- journal article
- clinical trial
- Published by Elsevier in British Journal of Anaesthesia
- Vol. 80 (1) , 7-10
- https://doi.org/10.1093/bja/80.1.7
Abstract
We have compared intermittent bolus and continuous infusion of extradural local anaesthetic for pain relief in a randomized, double-blind study of 48 patients who underwent major abdominal gynaecological surgery. Each patient received 5 ml of 0.375% bupivacaine hourly, either as a bolus over 5 min or as a constant infusion. Patients who received the intermittent administration technique maintained a more extensive sensory block, reported marginally better analgesia and had a lower requirement for rescue medication. The intermittent bolus technique was not associated with an increase in side effects.Keywords
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