Alkoxide-Induced Reaction of 1-[(Trimethylsilyl)-Methyl]Azoles with Imines and Carbonyl Compounds
- 1 July 1989
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 19 (11) , 2219-2227
- https://doi.org/10.1080/00397918908052618
Abstract
t-BuOK-induced reaction of 1-[(trimethylsilyl)methyl]-1,2,4-triazole with imines to yield (triazol-1- yl)ethylamines and (triazol-5-yl)methylamines was explored. Also, alkoxide-induced desilylation of 1-[(trimethylsilyl)methyl]azoles in the presence of carbonyl compounds was demonstrated, and (-BuOK and potassium trimethylsilanolate were found to be effective in this reaction.Keywords
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