STIMULATION OF INSULIN SECRETION BY GLUCAGON AND SECRETIN
- 1 April 1968
- journal article
- research article
- Published by Oxford University Press (OUP) in Acta Endocrinologica
- Vol. 57 (4) , 578-584
- https://doi.org/10.1530/acta.0.0570578
Abstract
Intravenous injection of 1.0 mg glucagon brings about a marked increase in the serum concentration of insulin in normal subjects. This increase sets in before the increase in blood sugar and reaches a peak 2[long dash]8 min. after the injection. Intravenous injection of 75 units secretin also results in a rapid increase in the serum concentration of insulin in normal subjects. This increase is less marked than that following glucagon and reaches its peak 3[long dash]4 min. after the injection. Glucagon and secretin contribute to the pronounced increase in insulin concentration during oral administration of glucose.This publication has 2 references indexed in Scilit:
- The Effects of Secretin, Pancreozymin, and Gastrin on Insulin and Glucagon Secretion in Anesthetized Dogs *Journal of Clinical Investigation, 1967
- Stimulation of Insulin Secretion by PancreozyminDiabetes, 1967