1H MR spectroscopy of brain tumours and masses
- 1 May 2003
- journal article
- review article
- Published by Wiley in NMR in Biomedicine
- Vol. 16 (3) , 123-131
- https://doi.org/10.1002/nbm.822
Abstract
Accurate diagnosis is essential for optimum management and treatment of patients with brain tumours. Proton magnetic resonance spectroscopy (1H MRS) provides information non‐invasively on tumour biochemistry and has been shown to provide important additional information to that obtained by conventional radiology. We review the current status of 1H MRS in classifying brain tumour type and grade, for monitoring response to therapy and progression to higher grade, and as a molecular imaging technique for determining tumour extent for treatment planning. Copyright © 2003 John Wiley & Sons, Ltd.Keywords
This publication has 69 references indexed in Scilit:
- Detection of elevated glutathione in meningiomas by quantitative in vivo1H MRSMagnetic Resonance in Medicine, 2003
- Clinical application of proton magnetic resonance spectroscopy in the diagnosis of intracranial mass lesionsNeuroradiology, 2002
- In vivo differentiation of astrocytic brain tumors and isolated demyelinating lesions of the type seen in multiple sclerosis using 1H magnetic resonance spectroscopic imagingAnnals of Neurology, 1998
- Increased choline signal coinciding with malignant degeneration of cerebral gliomas: a serial proton magnetic resonance spectroscopy imaging studyJournal of Neurosurgery, 1997
- Automated classification of human brain tumours by neural network analysis using in vivo H magnetic resonance spectroscopic metabolite phenotypesNeuroReport, 1996
- Proton chemical shift imaging, metabolic maps, and single voxel spectroscopy of glial brain tumorsMagnetic Resonance Materials in Physics, Biology and Medicine, 1996
- Continuing Ischemic Damage After Acute Middle Cerebral Artery Infarction in Humans Demonstrated by Short-Echo Proton SpectroscopyStroke, 1995
- Determination of proton metabolite concentrations and relaxation parameters in normal human brain and intracranial tumoursNMR in Biomedicine, 1995
- Choline‐Containing Compounds in Human Astrocytomas Studied by 1H NMR Spectroscopy In Vivo and In VitroJournal of Neurochemistry, 1994
- Complications of CT-guided stereotactic biopsy of intra-axial brain lesionsJournal of Neurosurgery, 1994