Increased endothelin concentration in CSF from patients with subarachnoid hemorrhage
- 1 June 1990
- journal article
- research article
- Published by Hindawi Limited in Acta Neurologica Scandinavica
- Vol. 81 (6) , 553-554
- https://doi.org/10.1111/j.1600-0404.1990.tb01018.x
Abstract
A considerable quantity of endothelin-like immunoreactivity was demonstrated as present in the CSF of patients with subarachnoid hemorrhage. The endothelin levels in the CSF raised from 0.4 ± 0.2 (Mean ± SD) pmol/L at Day 0-1 to 2.2 ± 0.6 pmol/L at Day 6 and the levels decreased gradually. The result suggest that endothelin may contribute the generation of vasospasm often observed in subarachnoid hemorrhage.Keywords
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