Metabolism and Metabolic Effects of Halopurine Nucleosides in Tumor Cells in Culture
- 1 February 1985
- journal article
- plenary lectures
- Published by Taylor & Francis in Nucleosides and Nucleotides
- Vol. 4 (1-2) , 107-116
- https://doi.org/10.1080/07328318508077834
Abstract
Within a series of halo derivatives of adenosine, deoxyadenosine and arabinosyladenine attempts have been made to correlate structure with cytotoxicity, substrate activity for adenosine deaminase and nucleoside kinases, and efficacy of the corresponding nucleotides against target enzymes.Keywords
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