Myocardial Coefficient of Oxygen Utilization

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Abstract
An analysis of blood oxygen values, coronary blood flow, and left ventricular oxygen consumption has been made on data obtained from 120 experiments on normal anesthetized dogs by using the N2O method for estimating coronary flow. The arterial oxygen content was shown to have a positive linear relationship to the myocardial arteriovenous oxygen difference (A-V,O2), but a negative linear relationship to coronary flow. The coefficient of oxygen utilization showed a positive linear regression with arterial oxygen-content values above 20 volumes per cent, but an inverse relationship with arterial oxygen values below 20 volumes per cent. The significance of these relationships in the regulation of coronary flow is discussed.

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