Effect of Brain Hormone from Bombyx mori on Metamorphosis of Calliphora erythrocephala

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Abstract
Appropriate extraction of brains and pupae of Bombyx mori yielded active brain hormone and ecdysone respectively. When various concentrations of these 2 hormones were introduced alone and in combination into isolated larval abdomens of Calliphora erythrocephala, pupation occurred when brain hormone was added to concentrations of ecdysone which would not induce pupation alone. (Pupation was not induced by brain hormone alone.) Brain hormone therefore may have a direct action on the tissues when acting synergistically with ecdysone in addition to its tropic action on the prothoracic gland.

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