Design, Synthesis, and Pharmacological Characterization of 4-[4,4-Dimethyl-3-(4-hydroxybutyl)-5-oxo-2-thioxo-1-imidazolidinyl]- 2-iodobenzonitrile as a High-Affinity Nonsteroidal Androgen Receptor Ligand
- 1 August 2000
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Medicinal Chemistry
- Vol. 43 (17) , 3344-3347
- https://doi.org/10.1021/jm000163y
Abstract
No abstract availableKeywords
This publication has 10 references indexed in Scilit:
- Distinguishing Androgen Receptor Agonists and Antagonists: Distinct Mechanisms of Activation by Medroxyprogesterone Acetate and DihydrotestosteroneMolecular Endocrinology, 1999
- Androgen receptor status of lymph node metastases from prostate cancerThe Prostate, 1996
- Specific steroid response from a nonspecific DNA elementThe Journal of Steroid Biochemistry and Molecular Biology, 1994
- Non-steroidal antiandrogens: Synthesis and biological profile of high-affinity ligands for the androgen receptorThe Journal of Steroid Biochemistry and Molecular Biology, 1994
- Molecular Analysis of the Androgen ReceptorAnnals of the New York Academy of Sciences, 1991
- Multiple Components of a Complex Androgen-Dependent EnhancerMolecular Endocrinology, 1991
- A simple phase-extraction assay for chloramphenicol acyltransferase activityGene, 1988
- Global Sea Level and Earth RotationScience, 1988
- The use of a hydroxylapatite-filter steroid receptor assay method in the study of the modulation of androgen receptor interactionJournal of Steroid Biochemistry, 1984
- The use of radioactive 7α, 17α‐dimethyl‐19‐nortestosterone (mibolerone) in the assay of androgen receptorsThe Prostate, 1984