Congenital hydrocephalus and cerebellar agenesis

Abstract
In a sibship of 3 brothers, 2 expired shortly after birth with congenital hydrocephalus, and necropsy of 1 revealed cerebellar agenesis and absence of the foramina of Luschka and Magendie. The non-specificity of the Dandy-Walker anomaly is discussed. The present patients apparently demonstrate another form of heritable hydrocephalus, possibly on an X-linked recessive basis.