Determination of blood serum potassium by an improved sodium cobaltinitrite method
- 1 January 1953
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 53 (2) , 213-217
- https://doi.org/10.1042/bj0530213
Abstract
The low accuracy of many methods of estimating serum K based on the Na cobaltinitrite procedure of Kramer and Tisdall is due mainly to 3 factors: the dilution of the serum with water, which can lead to as much as 20% of the K remaining unprecipitated owing to the solubility of K Na cabaltinitrite; allowing insufficient time for the precipitation of K; and dissolving some of the precipitate during washing. Modification of these and other factors has given a convenient method of improved accuracy. The results of replicate detns. agree closely, their standard deviation not exceeding 1% of their mean value, and the recovery of added K is satisfactory.Keywords
This publication has 1 reference indexed in Scilit:
- Colorimetric determination of potassium by Folin-Ciocalteu phenol reagentBiochemical Journal, 1949