Colposcopic findings of gland openings in cervical carcinoma: Their histological backgrounds

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Abstract
During the past 8 years 1501 colposcopies were performed paying a special attention to cervical glands for diagnosis of cervical intra‐epithelial neoplasia (CIN) and carcinoma. Normal openings could exclude these diseases at the error rate of only 5.1%, while atypical openings could identify them at the high confidence rate of 96.3%. False positive evaluations were mostly attributable to a marked degree of squamous metaplasia in the glands. The absence of gland openings in the main portion of the lesions amounted to 88.6% in invasive carcinomas but to only 12.4% in CIN. Adenoma malignum was a highly characteristic exception.

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