HEALING OF A CRUSH INJURY IN RAT STRIATED-MUSCLE .3. MICRO-ANGIOGRAPHICAL STUDY OF EFFECT OF EARLY MOBILIZATION AND IMMOBILIZATION ON CAPILLARY INGROWTH

  • 1 January 1976
    • journal article
    • research article
    • Vol. 84  (1) , 85-94
Abstract
Vascular ingrowth into the injured area of a partially crushed gastrocnemius muscle was studied by micro-angiography 2-14 days after the trauma in 40 rats treated by mobilization or immobilization. In mobilized muscles, the sprouting of new new capillaries occurred more rapidly and intensively than in injured muscles treated by immobilization. The sequence of events was slightly delayed if mobilization was started after immobilization for 2 days. The speed and intensity of tissue repair, as studied histologically, was directly correlated with vascular ingrowth, expecially during the 1st wk.

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