Prognostic Value of Contralateral Renal Plasma Flow in Renovascular Hypertension

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Abstract
Seventy-one hypertensive patients underwent differential renal function studies with use of urea,p-aminohippurate inulin infusion. All had surgery and 55 had proved unilateral renovascular cause for high blood pressure. Of these, 21 were cured, 20 were improved, and 14 were not affected by the surgical procedures. Cured patients had a mean renal plasma flow (RPF) to the contralateral kidney of 312 ± 24 ml/min. The value was 285 ± 19 ml/min for improved patients and 217 ± 20 ml/min for patients unchanged by surgery. The mean contralateral RPF for cured and improved patients differed significantly (P= 0.01) from that of the failure patients. These differences remained significant when calculated for atherosclerotic patients alone. Although overlap was present, these data will aid in exclusion of atherosclerotic patients of doubtful prognosis from low-yield renovascular surgical procedures.