New Bitter Diterpenes, Rabdosianone I and II, Isolated fromIsodon japonicusHara
- 1 January 1999
- journal article
- Published by Oxford University Press (OUP) in Bioscience, Biotechnology, and Biochemistry
- Vol. 63 (3) , 524-529
- https://doi.org/10.1271/bbb.63.524
Abstract
The new bitter diterpenes, rabdosianone I (C20H24O5) and II (C22H28O6), were isolated from Isodon japonicus (Japanese name, enmeiso), and their structures were elucidated by spectroscopic methods. Electrophysiological experiments were performed to compare rabdosianone I with quinine. The taste responses of chorda tympani nerves to rabdosianone I were smaller than those to quinine in Wistar rats.Keywords
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