D-amino acids as novel P2/P3 ligands for inhibitors of HIV-1 protease
- 1 June 1994
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 4 (11) , 1391-1396
- https://doi.org/10.1016/s0960-894x(01)80368-1
Abstract
No abstract availableKeywords
This publication has 11 references indexed in Scilit:
- Endothelin eceptor Ligands. Multiple D-Amino acid replacement net approachBioorganic & Medicinal Chemistry Letters, 1993
- Cyclic sulfolanes as novel and high-affinity P2 ligands for HIV-1 protease inhibitorsJournal of Medicinal Chemistry, 1993
- 3'-Tetrahydrofuranylglycine as a novel, unnatural amino acid surrogate for asparagine in the design of inhibitors of the HIV proteaseJournal of the American Chemical Society, 1993
- The HIV-1 Protease as a Therapeutic Target for AIDSAIDS Research and Human Retroviruses, 1992
- Kynostatin (KNI-227 and -272, highly potent anti-HIV agents: conformationally constrained tripeptide inhibitors of HIV protease containing allophenylnorstatine.CHEMICAL & PHARMACEUTICAL BULLETIN, 1992
- Sulfones as peptide bond isosteresTetrahedron Letters, 1991
- Ro-31-8959/003Drugs of the Future, 1991
- Mechanism of formation of serine β-lactones by Mitsunobu cyclization: synthesis and use of L-serine stereospecifically labelled with deuterium at C-3Canadian Journal of Chemistry, 1986
- Conversion of serine to stereochemically pure .beta.-substituted .alpha.-amino acids via .beta.-lactonesJournal of the American Chemical Society, 1985
- Chemoselective oxidation of sulfides to sulfones with potassium hydrogen persulfateTetrahedron Letters, 1981