FUCOSIDOSIS - ULTRASTRUCTURAL-STUDY OF CONJUNCTIVA AND SKIN AND ENZYME ANALYSIS OF TEARS

  • 1 January 1976
    • journal article
    • research article
    • Vol. 15  (8) , 626-639
Abstract
Conjunctival and skin biopsies from 2 new patients with fucosidosis were studied by EM. In both tissues the connective tissue cells and the capillary endothelial cells were filled with single membrane limited inclusions of 2 types: clear inclusions containing a fibrillogranular reticulum, and dark inclusions with a dense granular material. Specific stainings in ultrastructure suggest the these inclusions contain oligosaccharide chains. The ultrastructural aspect is characteristic for fucosidosis. Enzyme studies on tears realize an easy and secure technique for the diagnosis of the disease.

This publication has 2 references indexed in Scilit: