Total Synthesis of (±)-Virantmycin and Determination of Its Stereochemistry

Abstract
The stereospecific total synthesis of (±)-virantmycin (1) and its diastereomer (±)-2 were efficiently achieved, featuring an intramolecular nitrene-addition reaction as the key step, without ambiguity in the relative stereochemistry at the two chiral centers (C-2 and C-3).

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