PROBABLE HISTAMINE LIBERATION WITH ATRACURIUM
Open Access
- 1 August 1985
- journal article
- case report
- Published by Elsevier in British Journal of Anaesthesia
- Vol. 57 (8) , 811-813
- https://doi.org/10.1093/bja/57.8.811
Abstract
An histaminoid reaction after the administration of thiopentone and atracurium is described. Serial blood sampling showed no evidence of complement activation. Intradermal testing 6 weeks later yielded a positive result with atracurium (1 in 1000), but not with thiopentone. The clinical course of the reaction and the subsequent investigations suggest a direct pharmacological liberation of histamine.Keywords
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