Structure-Based Discovery of Potassium Channel Blockers from Natural Products: Virtual Screening and Electrophysiological Assay Testing
- 30 November 2003
- journal article
- Published by Elsevier in Chemistry & Biology
- Vol. 10 (11) , 1103-1113
- https://doi.org/10.1016/j.chembiol.2003.10.011
Abstract
No abstract availableKeywords
This publication has 57 references indexed in Scilit:
- Calculating Partition Coefficients of Peptides by the Addition MethodJournal of Molecular Modeling, 1999
- Sustained potassium currents in maturing CA1 hippocampal neuronesDevelopmental Brain Research, 1998
- The Structure of the Potassium Channel: Molecular Basis of K + Conduction and SelectivityScience, 1998
- Structural Conservation in Prokaryotic and Eukaryotic Potassium ChannelsScience, 1998
- Purification, Characterization, and Synthesis of an Inward-Rectifier K+ Channel Inhibitor from Scorpion VenomBiochemistry, 1997
- Pharmacology of Potassium ChannelsPublished by Elsevier ,1997
- A Strongly Interacting Pair of Residues on the Contact Surface of Charybdotoxin and a Shaker K+ ChannelNeuron, 1996
- Influence of protein surface charge on the bimolecular kinetics of a potassium channel peptide inhibitorBiochemistry, 1993
- Analysis of the blocking activity of charybdotoxin homologs and iodinated derivatives against Ca2+-Activated K+ channelsThe Journal of Membrane Biology, 1989
- The protein data bank: A computer-based archival file for macromolecular structuresJournal of Molecular Biology, 1977