Calcium Overload - An Important Cellular Mechanism in Hypertension and Arteriosclerosis
- 1 January 1992
- journal article
- review article
- Published by Springer Nature in Drugs
- Vol. 44 (Supplement) , 23-30
- https://doi.org/10.2165/00003495-199200441-00005
Abstract
Arterial hypertension and arteriosclerosis are dramatic consequences of vascular calcium overload. Acute intracellular calcium overload of vascular smooth muscle cells produces hypercontractility....Keywords
This publication has 14 references indexed in Scilit:
- Calcium — a Neglected Key Factor in Arteriosclerosis. The Pathogenetic Role of Arterial Calcium Overload and Its Prevention by Calcium AntagonistsAnnals of Medicine, 1991
- Excessive mural calcium overload — A predominant causal factor in the development of stenosing coronary plaques in humansCardiovascular Drugs and Therapy, 1990
- Hypertension and atherosclerosis.1990
- Cellular Mechanisms Regulating [Ca2+]i Smooth MuscleAnnual Review of Physiology, 1989
- Antihypertensive and arterial anticalcinotic effects of calcium antagonistsThe American Journal of Cardiology, 1986
- Experimental basis of the long-term therapy of arterial hypertension with calcium antagonistsThe American Journal of Cardiology, 1985
- Calcium channel-blocking drugs: a novel intervention for the treatment of cardiac disease. Introduction.1983
- Specific Pharmacology of Calcium in Myocardium, Cardiac Pacemakers, and Vascular Smooth MuscleAnnual Review of Pharmacology and Toxicology, 1977
- [Electromechanical uncoupling of vascular smooth muscle as the basic principle of coronary dilatation by 4-(2'-nitrophenyl-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid dimethyl ester (BAY a 1040, Nifedipine). 1. The significance of Ca ++ ions for the bioelectrical and mechanical activity of smooth muscle].1972
- [On the action mechanism of new coronary dilators with simultaneous oxygen saving myocardial effects, Prenylamine and Iproveratril. 1].1967