Repetitive Exon 45/46-Related Sequences of Human Ca2+ Channel α1C Subunit Gene

Abstract
We found in the Ca2+ channel α1C subunit gene a new repetitive element of three paired exon 45/46-related sequences. We also identified a new exon 45/46-related sequence in the human genome and mapped it by fluorescence in situ hybridization to the 12p11.2 and 12p13.2-p13.1 bands. These positions are not recognized by DNA probes generated from the 5′- and 3′-terminal regions of the α1C gene. A possible existence of a new genomic homologue of the α1C subunit gene is discussed.