Influnce of Insulin on Uptake of Monosaccharides by the isolated Rat Diaphragm

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Abstract
The uptake of D-galactose, D-xylose, and L-arabinose by the isolated rat diaphragm is such as can be attributed to equilibration with extracellular fluid. The uptake of D-glucose and D-fructose exceeds that attributable to diffusion while the uptake of D-arabinose does not approach that of the other pentoses. Insulin enhances the uptake of D-glucose, D-fructose, D-galactose, and L-arabinose. The data support the hypothesis that insulin acts on some mechanism other than the hexokinase reaction.